Management (WARM)
Goals of care
- Maintaining normothermia (temperature) between 36.5-37.5
- Maintain thermoregulation
- Prevent hypothermia
- Promote thermoregulation
- Prevent temperature instability
- Risk of impaired thermoregulation
- Risk of temperature instability
Temperature instability- presumed sepsis
- Prevent risk for infection related to immature immune system
- Prevent risk for infection related to exposure to pathogens
- Prevent risk for infection related to immature immune system and exposure to pathogens
Thermoregulation is crucial in neonates because their immature bodies lose heat quickly and cannot regulate temperature effectively, putting them at risk of hypothermia, metabolic stress, and serious complications.
Hypothermia is when an infant’s temperature is below normal range (36.5°C). Hypothermia can also cause vasoconstriction, further impairing oxygen delivery Essential for preventing hypothermia, especially in vulnerable and preterm infants as cold stress which can worsen respiratory distress, leading to exacerbate hypoxia and hypoglycaemia. If an infant becomes hypothermic, they will increase their metabolic demands, therefore increasing the glucose consumption. Premature infants have less ability to regulate body temperature, making thermoregulation critical for their overall health and stability. They have limited fat stores and immature thermoregulation, making them prone to heat loss.
Hyperthermia is when an infant’s temperature is above normal range (>37.5°C), this can be caused by environmental factors like excessive clothing or a warm environment, rather than an underlying disease.
Strategies
Maintaining normothermia is critical in the care of premature or hemodynamically unstable neonates, as they are particularly vulnerable to heat loss. Effective thermal management helps prevent complications such as hypothermia, hypoglycaemia, and hypoxia.
Interventions
Interventions to support thermoregulation include the use of incubators, which provide a controlled and humidified environment; radiant warmers, which offer immediate warmth during procedures or resuscitation; and open cots with additional thermal aids for stable infants. Each method is selected based on the neonate’s condition, gestational age, and care requirements.
Incubators
Incubators provide a NTE which will minimise metabolic and oxygen expenditure. They are used to maintain a controlled thermal environment and enable visualisation of the hemodynamically unstable infant or preterm infants. Infants are generally nursed naked with nappy only, which enables visualisation, incubators can be used in manual mode were a desired Neutral Thermal Range (NTR) is set based on infants’ weight and hours of age or servo-controlled mode, where probe that is attached to the incubator is placed on the infant (generally abdomen) and the incubator will heat up or cool down to keep infant at desired (set) temperature.
Indications:
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- Prematurity – all preterm infants less than 32 weeks’ gestation
- And or less than 1800 grams
- Hemodynamically unstable sick term infant
- Respiratory distressed- nurse naked, enables visualisation of work of breathing (WOB), prone positioning- if not contraindicated (contraindications include un-monitored infant, umbilical lines)
- Nurse naked with nappy- enables visualisation of work of breathing (WOB)
- Phototherapy- enables maximum exposure of infant’s skin to lights
- Oxygen therapy- enables ambient oxygen titrated to infants needs to be circulated throughout incubator
- Humidity-can be used to deliver humidity to the preterm infant to prevent TEWL in the first 14 days of life.
Open cots
Open cots are used for haemodynamically stable infants.
Indications:
-
- Greater than 32 weeks’ gestation
- And or greater than 1800 grams
- Layers of clothing and blankets adjusted according to the infant’s needs
Radiant warms
Radiant warms provide infrared heat to warm the naked infant. The heat generated must offset the radiant heat lost by the infant to the environment. Can be used in either a manual mode or servo controlled.
Nowadays many radiant warmers are hybrid cots, that can be converted into incubators once infant is stabilised.
Indications:
-
- Suitable for stabilising infants.
- Infants requiring multiple procedures.
- Larger infants
(RCH 2020, Gardner et al 2021, Kain and Mannix 2023)
Monitoring temperature
Continuous or frequent monitoring of the neonate’s temperature is essential to ensure they remain within a safe thermal range and to promptly detect any signs of hypothermia or hyperthermia.
Monitor axillary temperature: On admission then, check temperature 4 hourly and adjust environmental conditions accordingly if temperature deviated from norm, then intervention required and reevaluate in one hour. if cold on admission check hourly & skin (vasoconstricted, cool periphery?) until normal & stable, adjust incubator accordingly. Behaviour – lethargic if cold?
Temperature below 36.5ºC- and being nursed in incubator within Neutral thermal range (NTR) increase incubator temperature by 0.5ºC hourly whilst checking axilla temperature hourly until 2 consecutive temperatures above 36.5ºC.
If nursed in an open cot then layers can be added whilst checking axilla temperature hourly until 2 consecutive temperatures above 36.5ºC.
Temperature above 37.5ºC- and being nursed in incubator within NTR decrease incubator temperature by 0.5ºC hourly whilst checking axilla temperature hourly until 2 consecutive temperatures between 36.5ºC and 37.5ºC.
If nursed in an open cot then layers can be removed whilst checking axilla temperature hourly until 2 consecutive temperatures between 36.5ºC and 37.5ºC.
Prevent heat loss of heat via radiation, convection, conduction & evaporation weigh using scales with warm wraps, warm stethoscope
If in incubator adjust settings to keep axillary temperature between 36.5-37.5°C. keep side doors closed of incubator during procedures use portholes or radiant warmer.
Minimise Heat Loss:
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- Use bubble wrap to prevent evaporative heat loss.
- Weigh using scales with warm wraps, warm stethoscope
- Provide hat and pre-warmed linen in the incubator
- Positioning to mins heat loss, flexed & supported reduces surface area
- Nesting
- Minimise handling, cluster cares
Skin to Skin Contact: Facilitate skin-to-skin contact (kangaroo care) in the hemodynamically stable infant when appropriate to support thermoregulation and bonding
Documentation: Record the infant’s temperature 4 hourly unless deviated from norm, then intervention required and reevaluate in one hour, note any deviations from normal and escalate accordingly
(RCH 2020, Gardner et al 2021, Kain and Mannix 2023)
Evaluation
-
- Normothermic, well perfused & warm skin including periphery, pink,
- Axillary temperature stabilizes within 36.5-37.5°C.
- Infant remains warm to touch with no signs of cold stress (e.g., hypoglycaemia, lethargy).
- Stable blood glucose levels (cold stress can exacerbate hypoglycaemia).
- Temperature stabilises within normal range, no signs cold stress.
(RCH 2020, Gardner et al 2021, Kain and Mannix 2023)
Complications Hypothermia may cause:
– Hypoxia
– Hypoglycaemia
– Acidosis
Managing the thermal environment in some more commonly seen SCN presentations
*** this is a guide only: Always refer to local policy and or guidelines to ensure you are practicing within hospital frameworks and your scope of practice***
Hypothermia
Cold stress causes an increases oxygen and glucose consumption as the infant tries to generate heat which can lead to hypoglycaemia & hypoxia.
Temperature less than 36.5ºC** rule out possible causes for hypothermia is it related to environmental factors- infant cold from admission, cold equipment (scales, cots not prewarmed, cold wraps), undergone multiple procedures, incubator not within NTR, Servo probe not correctly positioned, consider temperature instability related to possible sepsis.
Trouble shooting tips
- If nursed in incubator in NTE and cot is within NTR (based on infants’ weight & hours of age) then increase incubator temperature by 0.5ºC an hourly whilst checking axilla temperature hourly until 2 consecutive temperatures above 36.5ºC achieved.
- In nursed in incubator/ radiant warmer on servo control mode, reposition probe.
- If nursed in an open cot then layers (hat and or blanket and or cardigan) can be added whilst checking axilla temperature hourly until 2 consecutive temperatures above 36.5ºC achieved.
Hypoglycaemia
Maintain normothermia: it is crucial to keep the infant’s body temperature stable to prevent cold stress, which can increase metabolic demands and worsen hypoglycaemia. Utilise warming devices as necessary and monitor the infant’s temperature closely.
Respiratory Distress
Maintain normothermia for symptomatic unwell infants– nurse naked with nappy in an incubator, rationale for incubator and naked is to enable visualisation of work of breathing and colour. Incubator mode may be either nursing infant in their Neutral Thermal environment or on Servocontrol dependant on gestational age and local policy.
Septic workup- Blood cultures, FBE, U&E and CRP to rule out infection as underlying cause, commence Antibiotic therapy (first line benzyl penicillin and gentamicin) until blood culture returns approximately 48 hours.
Prematurity & SGA (< 1800 grams)
Premature infants have a larger body surface area relative to their weight and less fat, which makes it difficult for them to maintain body temperature. Proper thermoregulation is crucial to prevent hypothermia and related complications, including metabolic stress and respiratory difficulties.
Incubator: provides a controlled environment to maintain the infant’s temperature which will minimise metabolic and oxygen expenditure
Hyperbilirubinemia
Incubator with Bililights- Infant to be nursed in incubator naked with exception of nappy based on medical advice. If nappy on, must be low to enable maximum skin exposure in Neutral thermal environment.
Open cot with Biliblanket- Infant to be nursed in open cot naked (with exception of nappy based on medical advice), plying on Bili blanket, blankets and wraps to be placed over infant (infant not to be wrapped).
Phototherapy- At commencement of phototherapy monitor infants’ temperature hourly for the first 4 hours ensuring it remains within the normal range (36.5-37.5°C), adjust environmental conditions accordingly if temperature deviated from norm, when intervention required reevaluate in one hour.
Feeding Intolerance
Observe in incubator: nurse naked in supine position to enable visualisation of the abdomen in the hemodynamically unstable infant, rationale allows visualisation of abdomen and work of breathing in an all-ready compromised infant.
Suspected Sepsis
Temperature instability – infection must be considered,
- Septic workup, blood cultures on admission, CRP (raised if septic) & FBE (neutropenia if septic) & right shift of WCC (body pumping immature WCCs into circulation) prophylactic IV antibiotics for 36 hrs until cultures neg,
Antibiotic therapy
Initiate Empiric Antibiotics (Until GBS Status Confirmed): use of Prophylaxis Antibiotics (first line benzyl penicillin and gentamicin) until blood culture returns approximately 48 hours, then ceased or changed to target specific organisms.
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- Any infant that is unwell must be considered to have sepsis, have high index of suspicion for the possibility of sepsis
- Low threshold for commencing antibiotics
- Collecting Blood Culture prior to administration
- More infants treated than infected
- Consequences of untreated infection are devastating
- Start IV benzyl penicillin + gentamicin to cover common neonatal pathogens (GBS, E. coli)
- Monitor for signs of sepsis (temperature instability, worsening respiratory distress, poor feeding)
Maintain normothermia for symptomatic unwell infants– nurse naked with nappy in an incubator, rationale for incubator and naked is to enable visualisation of work of breathing and colour. Incubator mode may be either nursing infant in their Neutral Thermal environment (NTE) or on Servocontrol dependant on gestational age and local policy.
Evaluation:
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- Negative blood cultures and normal infection markers (CRP, WBC)
- No signs of sepsis (stable temperature, no increased respiratory distress, normal perfusion). stable vitals
- No signs of worsening condition infection, Antibiotics given as ordered until Blood culture results return at 48 hrs
- EBM given as available during mouth care, appropriately responsive according to medical condition
- High achievers: CRP< 2, FBE NAD
Neonatal Abstinence Syndrome (NAS)
Monitor Temperature: Frequent monitoring (4 hourly) of the infant’s temperature to assess for signs of hyperthermia. Neonates with NAS are prone to fluctuations in temperature due to irritability and withdrawal symptoms. Swaddling with a light muslin wrap can help regulate temperature and provide comfort, promoting better thermoregulation.
References
Gardner, S., Carter, B., Enzman-Hines, M. and Niermeyer, S. (2021) Merenstein and Gardner’s Handbook of Neonatal Intensive Care. Ninth Edition. Elsevier.
Kain, V., and Mannix, T. (2023). Neonatal Care for Nurses and Midwives. Principles for Practice. Second Edition. Elsevier.
The Royal Children’s Hospital [RCH] (2020). Assisted Thermoregulation. Clinical Guideline, The Royal Children’s Hospital Melbourne https://www.rch.org.au/rchcpg/hospital_clinical_guideline_index/Thermoregulation_in_the_Preterm_Infant/
World Health Organisation [WHO]. (1997) Thermal Protection of the Newborn: a practical guide. Maternal and newborn health/ safe motherhood unit division of reproductive health (technical support) World Health Organization. Geneva https://iris.who.int/bitstream/handle/10665/63986/WHO_RHT_MSM_97.2.pdf
Neutral thermal environment
Neutral thermal range